ObesityWeek: Setmelanotide (IMCIVREE™) Successfully Induced Weight Loss in Patients With Hypothalamic Obesity

Patients were able to stay away from food for a longer time. For some of the patients that was really changing their lives. They are back to normal and not obsessed with food all the time.

WeightControl.com Interview with:
Dr. Christian Roth, MD
Seattle Children’s Research Institute and Division of Endocrinology
Department of Pediatrics
University of Washington

Dr. Christian Roth, MD
Seattle Children’s Research Institute and Division of Endocrinology
Department of Pediatrics
University of Washington
Dr. Roth

WeightControl.com:  What is the background for this study? Would you briefly explain what is meant by Hypothalamic Obesity?

Response: Hypothalamic obesity is a different entity of obesity that is rare and very difficult to treat. It is an acquired form of obesity due to injury to the hypothalamus because of a brain tumor and/or its treatment. This causes an abrupt change in body weight regulation because tissues that are important for energy homeostasis are partially or completely removed.

Typically, these patients can’t control their appetite and within a very short time after surgery they gain weight quickly. Their energy expenditure is also very low. So even if they cut down on calorie intake, they are typically not able to lose weight.

Gender Differences in Weight Loss with Medical Treatments

females lost more weight than males with similar exposures to liraglutide, suggesting that body size may not be the only factor.

WeightControl.com Interview with:
A/Prof Samantha L Hocking | Associate Professor Diabetes NSW & ACT
Sydney School of Medicine (Central Clinical School)
Charles Perkins Centre
Faculty of Medicine and Health
President National Association of Clinical Obesity Services

WeightControl.com:  What is the background for this study? 

Response: Numerous studies have shown that the mean response to a weight loss intervention hides significant individual variation. There are biological and physiological differences between males and females so gender is a potential predictor of weight loss outcomes. 

PostPartum Instagram Pics Most Often Idealized Athletic Images

Women with lower body fat, and in fitness attire, are more likely to post images of themselves on Instagram than women of higher adiposity.

WeightControl.com Interview with:
Dr Megan Gow 
NHMRC Early Career Fellow
Research Dietitian and Senior Lecturer
The University of Sydney Children’s Hospital Westmead Clinical School
Adjunct Senior Lecturer, Women’s and Children’s Health, UNSW
Honorary Research Associate, Women’s and Children’s Health,
St George Hospital

WeightControl.com:  What is the background for this study? 

Response: Research has already established that Instagram use is associated with negative impacts on mood and body satisfaction in young women. However, Instagram is highly accessed by women of reproductive age. We assessed 600 images tagged with #postpartumbody systematically captured from Instagram and coded them using a predefined framework.

Lean Individuals Who Intentionally Lose Weight May Risk Diabetes and Inceased Weight Gain

Exercise is optimal for long-term weight control and prevention of type 2 diabetes when compared with low-calorie diet, low-calorie diet & exercise, fasting, commercial weight loss program, and diet pills.

WeightControl.com Interview with:
Dr. Keyi Si, PhD
Department of Nutrition
Harvard T.H. Chan School of Public Health

Dr. Keyi Si

WeightControl.com:  What is the background for this study? 

Response: Weight control is one of the primary and effective strategies for the prevention and management of obesity and related chronic diseases. However, long-term weight change and risks of developing type 2 diabetes following various weight loss strategies are understudied, especially among originally lean individuals.

New Weight Loss Model Targets Individual Response to Food Cues

Individuals who are high on food cue responsiveness typically have uncontrolled eating and ruminate (think) about food a lot of the time

WeightControl.com Interview with:

Dr. Kerri N. Boutelle, Ph.D
Department of Pediatrics
Herbert Wertheim School of Public Health and Human Longevity Science,
Department of Psychiatry
University of California, San Diego, La Jolla, California

WeightControl.com:  What is the background for this study?  What are the main findings?

Response: Behavioral weight loss, which includes nutrition and physical activity education and behavior therapy techniques (also called a lifestyle intervention), is not effective for all adults with overweight and obesity and of those who lose weight, the majority regain the weight back.  This suggests that there are unaddressed underlying mechanisms that impact the effectiveness of these interventions. 

We developed a novel weight loss model based on appetitive traits, called regulation of cues (roc), that targets improving responsiveness to hunger and satiety cues and decreasing responsiveness to food cues.  This is different than behavioral weight loss as it targets these internal control mechanisms while behavioral weight loss targets external control mechanisms.

After Bariatric Surgery, Women Advised to Wait At Least Two Years to Conceive

After bariatric surgery there is a rapid weight loss that may impair an adequate weight gain during pregnancy and may also be associated with nutritional deficiencies

WeightControl.com Interview with:
Dr Ana Carreira and Dr Bárbara Araújo
Department of Endocrinology and Metabolism
Centro Hospitalar e Universitário de Coimbra
Coimbra, Portuga

WeightControl.com:  What is the background for this study? 

Response: Bariatric surgery is increasingly common in women of reproductive age and reduces the risk of obesity-related comorbidities in pregnancy. However, women after bariatric surgery have an increased risk of having a baby who is underweight (small for gestational age, SGA). A shorter bariatric surgery-to-conception interval (BSCI) has been one of the factors associated with a higher risk of SGA neonates, and, as a result, women are generally advised to wait at least 12 months after bariatric surgery before trying to conceive. However, the optimal bariatric surgery-to-conception interval is yet to be determined, and current recommendation differ among scientific societies, with some advocating a minimum of 12months and others 18 or 24 months.

Restaurants Add Lower Calorie Options After Calorie Display Laws, But Keep Old Favorites on Menus

Our research suggests that restaurants are bringing lower-calorie options to their menus now that they are required to display calorie labels on their menus.

WeightControl.com Interview with:
Anna HGrummon PhD , Postdoctoral Fellow
Department of Nutrition
Harvard TH Chan School of Public Health

Anna-H.-Grummon
Dr. Grummon

WeightControl.com:  What is the background for this study?  What are the main findings?

Response: As of 2018, large chain restaurants in the US are required by law to display calorie information on their menus. A number of researchers have looked at how consumers respond to the new calorie labels. What was not yet known was how the industry responded to the calorie labeling law. Our study is the first to investigate whether nationwide rollout of the calorie labeling law spurred restaurants to change the types of foods they offer. We found that the rollout of the calorie labels appeared to prompt restaurants to introduce lower-calorie items to their menus, but did not spur changes to existing menu items.


WeightControl.com: What should readers take away from your report?

Response: Our research suggests that restaurants are bringing lower-calorie options to their menus now that they are required to display calorie labels on their menus. These new options could help Americans find foods that meet their health goals when they get take-out or dine at restaurants. 

At the same time, existing menu items did not change after the labels were rolled out. This suggests that additional policy changes might be needed to nudge restaurants to make these existing items healthier. The calorie labeling law is important in providing consumers with information about menu items that was hard to find previously. Future policies can build on this success.

WeightControl.com: What recommendations do you have for future research as a result of this work?

Response: Our study examined restaurant menus, not what consumers buy or eat. So we don’t yet know how these changes to menus will affect what consumers eat and drink at restaurants, or ultimately how this policy will affect health outcomes. Future studies can examine how consumers respond to both calorie labels and to changes in the types of items sold by restaurants.

WeightControl.com: Is there anything else you would like to add?

Response: Mandatory labelling may have spurred restaurants to introduce new, lower calorie items to their menus. These calorie labels also allow consumers to easily view the calorie count of their meal, information which was difficult to find before the law.

No disclosures.

Citation:

Grummon AH, Petimar J, Soto MJ, et al. Changes in Calorie Content of Menu Items at Large Chain Restaurants After Implementation of Calorie Labels. JAMA Netw Open. 2021;4(12):e2141353. doi:10.1001/jamanetworkopen.2021.41353

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