Reduction in Cancer Risk Following Bariatric Surgery

Dr. Rustgi Interview with:
Vinod K Rustgi, MD, MBA
Professor of Medicine
Clinical Director of Hepatology
Director, Center for Liver Diseases and Liver Masses
Professor of Epidemiology
Professor of Pathology and Laboratory Medicine
New Brunswick, NJ 08901  What is the background for this study?  What are the main findings?

Response: ‚ÄčObesity is a burgeoning problem in the USA and globally. It is estimated that over $100 billion are spent in healthcare expenditures each year on those patients with fatty liver disease related to obesity-induced problems.

Lifestyle modification is very difficult to achieve on a sustained basis. Insurance companies have strict criteria for bariatric surgery. Our study of a database of over 100 million lives spanning the years of 2007 to 2017 showed a marked reduction in all malignancies after bariatric surgery and particularly in obesity-related cancers such as colorectal, esophageal, pancreatic, ovarian, uterine, postmenopausal breast and kidney cancers. What should readers take away from your report?

Response: Maintaining a normal weight is an important factor in health. Obesity increases the risk of malignancy. This is the first study to quantify the marked reduction in malignancy risk achieved through weight loss via bariatric surgery. What recommendations do you have for future research as a result of this work?

1. Is there a critical amount of weight reduction?

2. Are there demographic variables of importance such as race,ethnicity, gender?

3. Are there greater benefits in older people who are more prone to malignancy?

There was no external funding for this research. None of the authors have any relevant disclosures.


Bariatric Surgery Reduces Cancer Risk in Adults with Nonalcoholic Fatty Liver Disease and Severe Obesity
Rustgi, Vinod K. et al.
Gastroenterology, Volume 0, Issue 0

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Last Updated on March 31, 2021 by weightcontrol