ObesityWeek: GLP-1 Therapy Increases Fat Metabolism as Well As Making You Eat Less

Treatment of obesity is more complicated than simply eat less and move more –  and these newer GLP-1 based therapies are increasing fat tissue metabolism as well as making you eat less.

WeightControl.com Interview with:
Prof Donal O’ Shea MB, BCh, BAO, MD, FRCPI, FRCP (UK)
UCD School of Medicine
UCD Health Sciences Centre
University College Dublin

WeightControl.com:  What is the background for this study? 

Response: Glucagon‐like peptide‐1 (GLP‐1) analogs are powerful weight‐loss treatments. These analogs are believed to act primarily by having a major impact on energy intake through delaying gastric emptying and promoting satiety.

We felt this was over simplistic and that it was likely that GLP-1 treatments also had an effect on the other side of the energy balance equation through increasing metabolic activity in fat tissue.