Tag: #ICO2022

Gender Differences in Weight Loss with Medical Treatments

females lost more weight than males with similar exposures to liraglutide, suggesting that body size may not be the only factor.

WeightControl.com Interview with:
A/Prof Samantha L Hocking | Associate Professor Diabetes NSW & ACT
Sydney School of Medicine (Central Clinical School)
Charles Perkins Centre
Faculty of Medicine and Health
President National Association of Clinical Obesity Services

WeightControl.com:  What is the background for this study? 

Response: Numerous studies have shown that the mean response to a weight loss intervention hides significant individual variation. There are biological and physiological differences between males and females so gender is a potential predictor of weight loss outcomes. 

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Genetic Platform Can Allow Some Meds to Be Repurposed for Obesity and Type 2 Diabetes

In the current project we developed genetically informed repurposed medications to tackle obesity and type 2 diabetes (T2D)

WeightControl.com Interview with:
Professor Murray Cairns. 
Sahar El Shair, PhD student
University of Newcastle, NSW, Australia

WeightControl.com:  What is the background for this study? 

Response: The background is that we want to improve global health by making a significant impact on chronic disease. Many of these complex disorders have a substantial genetic risk but this risk involves hundreds of genes (unlike the simple genetic disorders that people are more familiar with caused by a single gene) and manifests differently in different people.

To break through this problem we developed a platform for aggregating and scoring an individual’s risk for complex disorders in gene networks that can be modulated by drugs. This includes new drugs, existing drugs and those that are currently used for other conditions.  

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