WeightControl.com Interview with:
Matthew J. Landry, PhD, RDN, FAND, FAHA (he/him)
Assistant Professor
Department of Population Health & Disease Prevention
University of California, Irvine
WeightControl.com: What is the background for this study?
Response: Lifestyle interventions are the first-line treatment for obesity; however, not all participants achieve clinically significant weight loss.
As researchers and clinicians, we want to minimize patient burden, maximize clinical outcomes, and conserve constraints (budget & personnel).
Using data from a 12-month diet and weight loss intervention (DIETFITS), we examined 52 demographic, clinical, & psychosocial variables among 436 participants (BMI 28-40) to see if there are distinct subgroups of participants who were more or less successful in losing 5% weight by 12 months?
WeightControl.com: What are the main findings?
Response: Overall, 51% of participants achieved at least 5% weight loss at 12 months, with eight subgroups identified. Among racial/ethnic minority participants, the most successful subgroup (74% met the 5% weight loss threshold) were individuals with low levels of friend discouragement in making healthy changes coupled with low levels of emotional eating, whereas the least successful subgroup (20% met threshold) included those with high levels of emotional eating. Among non-Hispanic white participants, the most successful subgroup (73% met threshold) had high outcome expectations for making health improvements coupled with high levels of family encouragement in making healthy changes, whereas the least successful subgroup (39% met threshold) had low levels of family encouragement.
WeightControl.com: What recommendations do you have for future research as a result of this work?
Response: Future research should take the important step of understanding demographic, clinical, & psychosocial variables of their target population before intervening. Examining subgroups is the first step of a precision behavioral medicine paradigm aimed at identifying intervention targets that can increase the likelihood of success in behavioral weight loss treatment.
Disclosures:
Credit to this secondary analysis primary author Dr. Michele Patel ([email protected]). More details for the DIETFITS intervention are available at clinicaltrials.gov identifier: NCT01826591.
Citation: OBESITYWEEK23 October 2023 abstract
Identifying Subgroups that Vary in Weight Loss Success in the DIETFITS Trial using Signal Detection
Michele L. Patel, PhD, Instructor, Stanford University, Matthew J. Landry, PhD, RDN, FAND, FAHA, Priya Fielding-Singh, PhD, Astrid N. Zamora, PhD, MPH, Abby C. King, PhD, Christopher D. Gardner, PhD
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Last Updated on October 16, 2023 by weightcontrol