WeightControl.com: What are the main findings?
Response: The main findings from aged female mice and menopause mouse models demonstrate that daily 30-minute heat treatment protects against obesity and improves insulin sensitivity by increasing energy expenditure in brown adipose tissue, a key metabolically active organ.
WeightControl.com: What should readers take away from your report?
Response: Daily 30-minute heat treatment is safe and reduces aging-mediated tissue damage. It is a promising and effective therapeutic strategy to boost metabolism and reduce the risk of obesity and metabolic dysfunction. Moreover, this simple and accessible intervention can partially mimic the benefits of exercise, making it particularly valuable for individuals who may have limitations in their physical activity.
The findings highlight the potential of non-pharmacological approaches to enhance metabolic health and address age-related metabolic challenges. As we continue to explore the benefits of heat treatment, it may emerge as a critical tool in promoting healthy aging and improving the quality of life for aging populations.
WeightControl.com: What recommendations do you have for future research as a result of this work?
Response: Future research should focus on confirming the effects of heat treatment on the aging population, especially post-menopausal females, through human studies. Investigating the optimal duration and frequency of heat treatment for maximum metabolic benefits, as well as the potential long-term effects and safety of such interventions in humans, is also warranted. Finally, examining the combined effects of heat treatment with other lifestyle interventions, such as diet, could provide a more comprehensive approach to managing age-related metabolic decline.
WeightControl.com: Is there anything else you would like to add? Any disclosures?
Response: This abstract won the Emerging Leaders in Nutrition Science Poster Competition(ELPC) in Aging and Chronic Disease, 1st place.
Nothing to disclose. This study was funded by the University of Massachusetts Amherst.
Citation: Nutrition June 2024 Session: Nutritional Interventions and Metabolic Insights in Aging and Obesity (Poster Theater Flash Session 11)
(PTFS11-03-24) Hyperthermia Treatment Attenuates Diet-Induced Obesity and Insulin Resistance in Old Female and Ovariectomized Mice via TRPV1-Mediated Futile Calcium Cycling
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Last Updated on July 2, 2024 by weightcontrol