WeightControl.com Interview with:
Eric C. Nemec PharmD MEHP BCPS
Director of Research and Assessment
Associate Professor
Master of Physician Assistant Program
Sacred Heart University
Office location: 4 Hospital Plaza, Tandet Center, Stamford, CT 06902

WeightControl.com: What is the background for this study?
Response: When we started this project, we knew that glucagon-like peptide-1 receptor agonists (GLP-1RAs) were highly effective for weight loss; however, there was limited evidence regarding the sustainability of that weight loss after treatment cessation.
Our study systematically reviewed and meta-analyzed randomized controlled trials to determine the extent of weight regain after GLP-1RA discontinuation. The key finding was that significant weight is regained after stopping therapy, and this regain was proportional to the amount initially lost.
Last Updated on April 13, 2025 by weightcontrol