WeightControl.com: What are the main findings?
Response: Individuals with obesity will clearly benefit from losing a few pounds and the health benefits last even when the weight loss is temporary. However, lean individuals may have more weight gain and higher risks of developing type 2 diabetes if losing 10 or more pounds intentionally.
Exercise is optimal for long-term weight control and prevention of type 2 diabetes when compared with low-calorie diet, low-calorie diet & exercise, fasting, commercial weight loss program, and diet pills.
WeightControl.com: What should readers take away from your report?
Response: To reduce the risk of developing type 2 diabetes, individuals with obesity are recommended to take measures for weight control and management while whether lean individuals shall consider weight loss should be guided by medical or health indications.
WeightControl.com: What recommendations do you have for future research as a result of this work?
Response: Further research is needed to explore the mechanisms of weight regain after weight loss and the effects of different weight loss strategies on the risk of developing type 2 diabetes.
Si K, Hu Y, Wang M, Apovian CM, Chavarro JE, Sun Q (2022) Weight loss strategies, weight change, and type 2 diabetes in US health professionals: A cohort study. PLoS Med 19(9): e1004094. https://doi.org/10.1371/journal.pmed.1004094
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